Medical Information Only: This medication is not sold on this site. The information provided is for reference purposes only. Please consult your local physician or pharmacist for treatment.

Trifluoroperazine Hydrochloride: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Trifluoroperazine Hydrochloride - General Information

A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic. [PubChem]

 

Pharmacology of Trifluoroperazine Hydrochloride

Trifluoroperazine Hydrochloride is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Trifluoroperazine Hydrochloride has not been shown effective in the management of behaviorial complications in patients with mental retardation.

 

Trifluoroperazine Hydrochloride for patients

 

Trifluoroperazine Hydrochloride Interactions

No information provided.

 

Trifluoroperazine Hydrochloride Contraindications

A known hypersensitivity to phenothiazines, comatose or greatly depressed states due to central nervous system depressants and, in cases of existing blood dyscrasias, bone marrow depression and pre-existing liver damage.

 

Additional information about Trifluoroperazine Hydrochloride

Trifluoroperazine Hydrochloride Indication: For the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation. Mechanism Of Action: Trifluoroperazine Hydrochloride blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Trifluoperazine Synonyms: Not Available Drug Category: Antipsychotics; Antiemetics; Phenothiazines Drug Type: Small Molecule; Approved Other Brand Names containing Trifluoperazine: Apo-Trifluoperazine; Eskazine; Eskazinyl; Fluoperazine; Jatroneural; Modalina; Novo-Trifluzine; PMS Trifluoperazine; Stelazine; Stelazine Concentrate; Stellazine; Synklor; Terfluzine; Trazine; Trifluoperazin; Trifluoperazina; Trifluoperazine Dihydrochloride; Trifluoperazine HCl; Trifluoperazine Hydrochloride; Trifluoromethylperazine; Trifluoroperazine; Trifluoroperazine Dihydrochloride; Trifluoroperazine Hydrochloride; Trifluperazine; Triflurin; Trifluroperizine; Triftazin; Triftazine; Triperazine; Triphtazin; Triphtazine; Triphthasine; Triphthazine; Triphthazine Dihydrochloride; Tryptazine; Tryptazine Dihydrochloride; Absorption: Not Available Toxicity (Overdose): Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness. Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Trifluoroperazine Hydrochloride: Tablet OralSyrup Oral Chemical IUPAC Name: 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine Chemical Formula: C21H24F3N3S Trifluoperazine on Wikipedia: https://en.wikipedia.org/wiki/Trifluoperazine Organisms Affected: Humans and other mammals